Genes, Systems and Computation Seminar: AI models for regulatory genomics and spatial biology

Speaker: Christina Leslie

Location: To Be Arranged, Room NYU Langone Science Building : Seminar Room 103

Date: Tuesday, April 28, 2026

A little bit about Dr. Leslie, her lab and their research –

Develops computational and machine-learning methods to analyze high-throughput genomic data and model molecular networks that regulate core cellular processes (transcription, signaling, RNA processing, gene silencing). Studies cell-type–specific gene regulation, including transcription factor binding and chromatin accessibility, to understand how regulatory programs form, change, and are maintained during differentiation. Investigates post-transcriptional regulation, especially microRNA activity, RNA-binding proteins, and alternative polyadenylation, using advanced sequencing technologies and statistical modeling. Applies integrative cancer systems biology approaches that combine multi-omics data to identify regulatory drivers of tumors and model interactions between cancer cells and their microenvironment.