We are at Courant Institute, 251 Mercer St, New York, Phone: 212-992-7546
Largely speaking, we are interested in understanding molecular mechanisms of regulation
and mechanics of cell migration, mitosis and cell division and self-organization and assembly
principles of actin-microtubule-motor machines. We also work on how nuclei are positioned and
how their size is regulated.
Our major current projects are:
1. Detailed quantitative understanding of actin dynamics using in vitro systems (with Keren and Blanchoin/Thery labs).
2. Self-assembly, error correction and mechanics of mitotic spindle and cytokinesis (with Khodjakov and Wadsworth and Maresca labs).
3. Mechanisms of galvanotaxis (with Zhao lab).
4. Mechanisms of contraction in actin-myosin networks in vitro and in yeast cells (with Blanchoin/Thery, Keren and Laplante labs).
5. Positioning and size scaling of nuclei in multinucleated cells (with Baylies lab).
6. Mechanics and dynamics in microtubule-motor systems in Drosophila and Xenopus cells (with Gelfand and Burgess labs).
7. Collective cell migration (with Christiaen lab).