Publications:

A. Mogilner, G.Oster, Cell motility driven by actin polymerization, Biophysical Journal 71 , 3030-3045 (1996) preprint in pdf format

A. Mogilner, G.Oster, The physics of lamellipodial protrusion, European Biophysical Journal 25 , 47-53 (1996) preprint in pdf format

D. Bottino, A. Mogilner, T. Roberts, M. Stewart, G. Oster, How nematode sperm crawl, J. Cell Science 115 , 367-384 (2002)
preprint in pdf format

A. Mogilner, L. Edelstein-Keshet, Regulation of Actin Dynamics in Rapidly Moving Cells: A Quantitative Analysis. Biophys. J. 83 , 1237-1258 (2002)
preprint in pdf format

A. Mogilner, D. Verzi, A Simple 1-D Physical Model for the Crawling Nematode Sperm Cell. J. Stat. Phys. 110 , 1169-1189 (2003)
preprint in pdf format

A. Mogilner, G.Oster, Force generation by actin polymerization II: The elastic ratchet and tethered filaments. Biophysical Journal 84 , 1591-1605 (2003)
preprint in pdf format

H. P. Grimm, A. B. Verkhovsky, A. Mogilner, J.-J. Meister, Analysis of Actin Dynamics at the Leading Edge of Crawling Cells: Implications for the Shape of Keratocyte Lamellipodia. Eur. Biophys. J., 32, 563-577 (2003)
preprint in pdf format

C. Wolgemuth, A. Mogilner, G. Oster, The hydration dynamics of polyelectrolyte gels with applications to drug delivery and cell motility. Eur. Biophys. J., 33, 146-158 (2004)
preprint in pdf format

G. Civelekoglu-Scholey, A. Wayne Orr, I. Novak, J.-J. Meister, M.A. Schwartz, A. Mogilner, Model of coupled transient changes of Rac, Rho, adhesions and stress fibers alignment in endothelial cells responding to shear stress. J. Theor. Biol., 232 , 569-585 (2005)
preprint in pdf format

I. L. Novak, B. M. Slepchenko, A. Mogilner, L. M. Loew, Cooperativity between cell contractility and adhesion. Phys. Rev. Lett., 93 , 268109 (2004)
preprint in pdf format

B. Rubinstein, K. Jacobson, A. Mogilner, Multiscale Two-Dimensional Modeling of a Motile Simple-Shaped Cell. SIAM J. MMS, 3 413-439 (2005)
preprint in pdf format View the movies (based on the model of this paper) of the motile lamellipodial fragment here.
and of the turning lamellipodial fragment here.

B. Rubinstein, A. Mogilner, The Physics of Filopodial Protrusion. Biophys. J. , 89 782-795 (2005)
preprint in pdf format

S. Bohnet, R. Ananthakrishnan, A. Mogilner, J.-J. Meister, A. Verkhovsky, Weak force stalls protrusion at the leading edge of the lamellipodium. Biophys. J., 90 1810-1820 (2006)
preprint in pdf format

M. Karakozova, M. Kozak, C. C. L. Wong, A. Bailey, A. Mogilner, J. Yates, A. Kashina, Arginylation of beta actin regulates actin cytoskeleton and cell motility, Science, 313 192-196 (2006)
preprint in pdf format

M. Prass, K. Jacobson, A. Mogilner, M. Radmacher, Direct measurement of the lamellipodial protrusive force in migrating cell, J. Cell Biol., 174 767-772 (2006)
preprint in pdf format

K. Larripa, A. Mogilner, Transport of a 1D viscoelastic actin-myosin strip of gel as a model of a crawling cell. Physica A, 372 113-123 (2006)
preprint in pdf format

C. I. Lacayo, Z. Pincus, M. M. VanDuijn, C. A. Wilson, D. A. Fletcher, F. B. Gertler, A. Mogilner, J. A. Theriot, Emergence of Large-Scale Cell Morphology and Movement from Local Actin Filament Growth Dynamics, PLoS Biology, 5 e233 (2007)
preprint in pdf format

M. M. Kozlov, A. Mogilner, Model of polarization and bi-stability of cell fragments, Biophys. J., 93 3811-3819 (2007)
preprint in pdf format

J. Fass, C. Pak, J. Bamburg, A. Mogilner, Stochastic Simulation of Actin Dynamics Reveals the Role of Annealing and Fragmentation, J. Theor. Biol., 252 173-183 (2008)
preprint in pdf format

K. Keren, Z. Pincus, G. M. Allen, E. L. Barnhart, G. Marriott, A. Mogilner, J. A. Theriot, Mechanism of shape determination in motile cells, Nature, 453 475-480 (2008)
preprint in pdf format

I. L. Novak, B. M. Slepchenko, A. Mogilner, Quantitative analysis of G-actin transport in motile cells, Biophys. J., 95 1627-1638 (2007)
preprint in pdf format

Choi CK, Vicente-Manzanares M, Zareno J, Whitmore LA, Mogilner A, Horwitz AF. Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat. Cell Biol., 10 1039-1050(2008)
preprint in pdf format

B. Rubinstein, M. F. Fournier, K. Jacobson, A. Verkhovsky, A. Mogilner. Actin-myosin viscoelastic flow in the keratocyte lamellipod. Biophys. J., 97 1853-1863 (2009)
preprint in pdf format

Keren K, Yam PT, Kinkhabwala A, Mogilner A, Theriot J. Intracellular fluid flow in rapidly moving cells, Nature Cell Biol., 11 1219-1224 (2009). preprint in pdf format

M J Dayel, O Akin, M Landeryou, V I Risca, A Mogilner, R D Mullins, In Silico Reconstitution of Actin-Based Symmetry Breaking and Motility, PLoS Biology, 7e1000201 (2009). preprint in pdf format

A. Mogilner and B. Rubinstein, Actin disassembly `clock' and membrane tension determine cell shape and turning: mathematical model, J Phys: Condens Matter, 22 194118 (2010). preprint in pdf format

Erin L. Barnhart, Kun-Chun Lee, Kinneret Keren, Alex Mogilner, and Julie A. Theriot, An adhesion-dependent switch between mechanisms that determine motile cell shape, PLoS Biology, 9 e1001059 (2011). preprint in pdf format

Charles W. Wolgemuth, Jelena Stajic, and Alex Mogilner, Redundant mechanisms for stable cell locomotion revealed by minimal models, Biophys J, 101 545-553 (2011). preprint in pdf format

Noa Ofer, Alex Mogilner, and Kinneret Keren, Actin Disassembly Clock Determines Shape and Speed of Lamellipodial Fragments, PNAS, 108 20394-20399 (2011). preprint in pdf format

Catherine I. Lacayo, Paula A. G. Soneral, Jie Zhu, Mark A. Tsuchida, Matthew J. Footer, Frederick S. Soo, Yu Lu, Younan Xia, Alexander Mogilner, and Julie A. Theriot, Choosing Orientation: Influence of Cargo Geometry and ActA Polarization on Actin Tails. Mol. Biol. Cell, 23 614-629 (2012). preprint in pdf format

Erin M. Craig, David Van Goor, Paul Forscher and Alex Mogilner, Membrane tension, myosin force and actin turnover maintain actin treadmill in the nerve growth cone. Biophys J, 102 1503-1513 (2012). preprint in pdf format

Jie Zhu and Alex Mogilner, Mesoscopic model of actin-based propulsion. PLoS Comput Biol, 8 (11) e1002764. doi:10.1371/journal.pcbi.1002764 (2012). preprint in pdf format

Weiwei Luo, Cheng-han Yu, Zi Zhao Lieu, Jun Allard, Alex Mogilner, Michael P. Sheetz and Alexander D. Bershadsky, Analysis of the local organization and dynamics of cellular actin networks. J Cell Biol, 202 1057-1073 (2013). preprint in pdf format

Ben Fogelson and Alex Mogilner, Computational estimates of membrane flow and tension gradients in motile cells. PLoS One, 9 e84524 (2014). preprint in pdf format

Praveen Suraneni, Ben Fogelson, Boris Rubinstein, Philippe Noguera, Niels Volkmann, Dorit Hanein, Alex Mogilner, Rong Li. A Mechanism of Leading Edge Protrusion in the Absence of the Arp2/3 Complex. Mol Biol Cell, 26 901-12 (2015). preprint in pdf format

Erin L. Barnhart, Kun-Chun Lee, Greg M. Allen, Julie A. Theriot, Alex Mogilner The balance between cell-substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes. PNAS, 112 5045-50 (2015). preprint in pdf format

Craig E, Stricker J, Gardel M, Mogilner A. Model for adhesion clutch explains biphasic relationship between actin flow and traction at the cell leading edge. Phys Biol, 12 035002 (2015). preprint in pdf format

X Shao, Q Li, A Mogilner, A Bershadsky, GV Shivashankar. Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim. PNAS, 112 E2595-E2601 (2015). preprint in pdf format

Alexis J. Lomakin, Kun-Chun Lee, Sangyoon J. Han, Amy Bui, Michael Davidson, Alex Mogilner, Gaudenz Danuser. Competition of two distinct actin networks for actin defines a bistable switch for cell polarization. Nat Cell Biol, 17: 1435-45 (2015). preprint in pdf format

Guetta-Terrier C, Monzo P, Zhu J, Long H, Venkatraman L, Zhou Y, Wang P, Chew SY, Mogilner A, Ladoux B, Gauthier NC. Protrusive Waves Guide 3D Cell Migration along Nanofibers. J Cell Biol, 211: 683-701 (2015). preprint in pdf format

D.B. Oelz, B.Y. Rubinstein and A. Mogilner. A Combination of Actin Treadmilling and Cross-Linking Drives Contraction of Random Actomyosin Arrays. Biophys J, 109: 1818-29 (2015). preprint in pdf format

Zhu J, Mogilner A. Comparison of cell migration mechanical strategies in three-dimensional matrices: a computational study. Interface Focus, 6: 20160040 (2016). preprint in pdf format

Erin L. Barnhart, Jun Allard, Sunny S. Lou, Julie A. Theriot, Alex Mogilner. Adhesion-Dependent Wave Generation in Crawling Cells. Cur Biol, 27: 27-38 (2017). preprint in pdf format