The Mechanics and Mathematics of
Biological Growth
Alain Goriely,
Mathematics Department, Program in Applied Mathematics, and BIO5
Institute, University of Arizona, Tucson.
Growth is involved in many fundamental biological processes such as
morphogenesis, physiological regulation, or pathological
disorders. It is, in general, a process of enormous complexity
involving genetic, biochemical, and physical components at many
different scales and with complex interactions. In this talk, I will
consider the problem of modeling growth in elastic materials and
investigate its mechanical consequences. First, starting with simple
system in one two and three dimensions, I will show how to generalize
the classical theory of exact elasticity to include growth. Second, I
will show how growth affects both the geometry of a body by changing
typical length scales but also its mechanics by inducing incompatible
residual stresses. The competition between these two effects can be
used to regulate the physical properties of a material during regular
physiological conditions. It can also lead to interesting phenomena
such as cavitation and spontaneous instabilities in growing materials
which can be observed in simple physical and biological systems.